MUMBAI, India, Aug. 17 -- Intellectual Property India has published a patent application (202641093783 A) filed by Saveetha Institute Of Medical And Technical Sciences on August 03, 2026, for Development Of A Mucoadhesive Antioxidant In-Situ Gel For The Management Of Oral Lesions.
Inventors include Dr Kishorwara R; Dr Uma Maheswari T N; and Dr. Deepak Nallaswamy Veeraiyan.
The application for the patent was published on August 14, 2026, under issue no. 33/2026.
Abstract: The present invention discloses a highly stable, thermosensitive, and mucoadhesive in situ gel delivery system for the localized management of oral mucosal lesions, particularly oral leukoplakia. The formulation comprises a thermo-responsive polymeric vehicle synthesized by dispersing a poly(oxyethylene)-poly(oxypropylene) block copolymer (Pluronic) at a concentration of 20% w/v under cool conditions, embedding a high-potency, reconstituted therapeutic core consisting of a 1:10 mass ratio of lyophilized raspberry powder and pomegranate peel powder bioactives. The formulation is a low-viscosity liquid under cool handling conditions, allowing uniform coating of irregular mucosal lesions, but instantly transitions into a high-viscosity hydrogel matrix upon exposure to physiological oral temperatures(34°C to 37°C). The resulting system provides an enhanced mucoadhesive separation force that resists salivary clearance and mechanical tongue movements, ensuring sustained, targeted antioxidant delivery directly to the compromised soft tissues.
Disclaimer: Curated by HT Syndication.
