MUMBAI, India, Aug. 31 -- Intellectual Property India has published a patent application (202641096723 A) filed by Dr. Sujit Kumar Mohanty; Shaik Yasmine; Satyavolu Gnana Saritha; Pragallapati Lakshmi Vaibhavi; and Shri Vishnu College Of Pharmacy, Bhimavaram. on August 11, 2026, for Design And In-Silico Development Of Curcumin Bridged Gallic Acid As Potent Anticancer Agent.
Inventors include Dr. Sujit Kumar Mohanty; Shaik Yasmine; Satyavolu Gnana Saritha; and Pragallapati Lakshmi Vaibhavi.
The application for the patent was published on August 28, 2026, under issue no. 35/2026.
Abstract: The present invention relates to the field of medicinal chemistry and pharmaceutical sciences and, more particularly, to novel curcumin—gallic acid conjugates and their use as potential anticancer agents. The invention provides hybrid compounds comprising a curcumin moiety covalently linked to a gallic acid moiety through a suitable chemical linker, including but not limited to ester, amide, ether, carbamate, carbonate, or alkyl linkages, to generate new molecular entities with desirable physicochemical and pharmacological properties. The invention further encompasses the design, computational optimization, and in silico evaluation of the conjugates using molecular modeling, geometry optimization, molecular docking, molecular dynamics simulation, binding free energy calculations, and ADMET prediction against one or more cancer associated molecular targets.
Disclaimer: Curated by HT Syndication.
