MUMBAI, India, June 24 -- Intellectual Property India has published a patent application (202441097021 A) filed by Sudharsan Sukkampalayam Palanisamy; Kanika Revathi Jayaraj; and Balaji Sadhasivam on December 09, 2024, for Design And Development Of In Situ-Forming Injectable Hydrogels And Micro-Injector For Ease Of Admini.
Inventors include Sudharsan Sukkampalayam Palanisamy; Kanika Revathi Jayaraj; and Balaji Sadhasivam.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: 6. ABSTRACT OF THE INVENTION The global market for hydrogels in medical applications is expected to grow significantly, with estimates suggesting a CAGR of around 10-12% over the next several years. Regenerative medicine is a field of biomedical science that uses biological principles to restore function to damaged or diseased organs, tissues or cells. So designing injectable hydrogels that form in situ, adapts to tissue structure and function will help in regenerating the damaged tissues, such as bone, cartilage or skin even acts as drug carrier to deliver bioactive agents that foster the natural repair process and encapsulate and deliver cells. Our project aims to develop an in situ-forming injectable hydrogel for regenerative medicine and optimize the hydrogel in order to design and develop a desired in-situ material. Also develop a micro-injection for administration. Alginate dialdehyde is a partially oxidized product of sodium alginate which facilitates the formation of stable covalently crosslinked networks with gelatin in the presence of borax that· accelerates the reaction between gelatin and borax. For administration, 30 model of micro-injector is designed in Blender that features two distinct input channels, which allows for the simultaneous injection of two separate substances through a single output channel. Followed by 30 printing of the micro injector is carried out using polylactic acid. In situ-forming compatible injectable hydrogel systems, acts as an ideal strategy that focuses on significant reduction in the necessity for invasive procedures. Minimally invasive surgery is becoming more common and a good option for a variety of conditions. Studies show that minimally invasive surgenes using in situ hydrogels can reduce recovery times by up to 30% compared to traditional methods. It can reduce the length of a patient's recovery and rehabilitation period, and can improve their quality of life.
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