MUMBAI, India, June 30 -- Intellectual Property India has published a patent application (202641075039 A) filed by Mrs. Gudapati. Krupa Mai; and Vijaya Institute Of Pharmaceutical Sciences Women on June 17, 2026, for Design, Synthesis, And Characterization Of Benzidine And O- Tolidine Based Schiff Bases Using Different Synthetic Methods And Evaluation Of Their Antimicrobial Activity.
Inventors include Mrs. Gudapati. Krupa Mai; Mrs. Kancharla. Suneetha; Ms. Polukonda. Pujitha; Ms. Sundarapalli. Mohana Santhosh Kumari; Ms. Battina. Manju Sai; Ms. Chikkulla. Kavya; and Ms. Suragani. Pavali.
The application for the patent was published on June 26, 2026, under issue no. 26/2026.
Abstract: ABSTRACT [0025] A significant class of chemical compounds known as Schiff bases is distinguished by the presence of an azomethine (-C=N-) functional group that is created when primary amines condense with aldehydes. Schiff bases were possessing many biological activities, especially their antibacterial qualities, have drawn a lot of interest in medicinal chemistry because of their structural adaptability and simplicity of synthesis. The creation of new antimicrobial drugs with enhanced efficacy and safety profiles is required due to the growing incidence of microbial resistance to traditional antibiotics. The design, synthesis, and characterization of new Schiff bases made from certain aromatic aldehydes and amines is the main aim of this work, to verify their structural identity, the produced compounds are evaluated using a variety of analytical methods, including melting point determination, thin-layer chromatography (TLC), infrared spectroscopy (IR). Standard microbiological techniques are used to assess the synthetic compounds antibacterial effectiveness against specific bacterial and fungal species. The goal of the research is to find interesting Schiff base derivatives with possible antibacterial uses and investigate structure– activity connections.
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