MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202611106806 A) filed by Panipat Institute Of Engineering And Technology Piet on September 04, 2026, for Curcumin-Loaded Bile Salt-Modified Vesicular Gel Composition For Topical Delivery And Method Of Preparation Thereof.
Inventors include Dr. Daisy Arora; and Dr. Arti Soni.
The application for the patent was published on October 23, 2026, under issue no. 43/2026.
Abstract: [058] The present invention relates to a curcumin-loaded bile salt-modified vesicular gel composition for topical delivery and a method for preparation thereof. The composition comprises curcumin-loaded vesicles formed from a non-ionic surfactant, cholesterol and a bile salt, dispersed in a carbomer-based gel containing a humectant and a neutralizing agent. The vesicles are prepared by thin-film hydration comprising organic dissolution of curcumin, surfactant and cholesterol, solvent removal, hydration with bile salt-containing buffer, size reduction and purification. Formulation variables are selectable with reference to vesicle size, entrapment efficiency and polydispersity index. Incorporation of the vesicles into the gel provides a skin-compatible topical dosage form exhibiting controlled curcumin release, enhanced skin permeation and increased skin deposition relative to a conventional curcumin gel, while retaining antioxidant activity. The composition is particularly suitable for localized topical delivery of curcumin in plaque psoriasis and related dermatological applications. Accompanied Drawing [FIGS. 1-8]
Disclaimer: Curated by HT Syndication.
