MUMBAI, India, June 26 -- Intellectual Property India has published a patent application (202631070124 A) filed by National Institute Of Technology Patna on June 04, 2026, for Coumarin-Ferrocene Probe Modified Gold Electrode Platform For Electrochemical Histamine Detection.
Inventors include Jha, Niki Sweta; and Rai, Anupama.
The application for the patent was published on June 19, 2026, under issue no. 25/2026.
Abstract: The present invention relates to an electrochemical sensing platform for detection of histamine using probe-modified gold electrode architectures comprising coumarin- ferrocene derivative probes. The sensing platform comprises a gold electrode associated with a probe layer comprising ferrocenyl-coumarin (FC), dihydropyrazole ferrocenyl-coumarin (DPFC), or combinations thereof, wherein interaction with histamine generates a measurable electrochemical response. Histamine detection is performed using electrochemical techniques including cyclic voltammetry and differential pulse voltammetry under acidic buffer conditions. The sensing platform exhibits concentration-dependent electrochemical response enabling histamine quantification at low concentration ranges. Compared to conventional histamine detection approaches, the disclosed platform provides simplified electrochemical analysis, improved sensitivity, enhanced selectivity, and reduced electrode performance deterioration during sensing. The invention is applicable in food quality monitoring, analytical chemistry, and biomedical analysis.
Disclaimer: Curated by HT Syndication.
