Intellectual Property India Publishes Patent Application for Compound Having Substance That Has Affinity For Soluble Protein, Cleavable Moiety, And Reactive Group, Or Salt Thereof

MUMBAI, India, July 24 -- Intellectual Property India has published a patent application (202418063794 A) filed by Ajinomoto Co. , Inc. on August 23, 2024, for Compound Having Substance That Has Affinity For Soluble Protein, Cleavable Moiety, And Reactive Group, Or Salt Thereof.

Inventors include Yamada, Kei; Matsuda, Yutaka; Fujii, Tomohiro; Shikida, Natsuki Number; Yuji, Reiko; Shimbo, Kazutaka; and Ito, Yuji Filed On.

The application for the patent was published on July 17, 2026, under issue no. 29/2026.

Abstract: The present invention provides a technique enabling modification of a soluble protein and in particular regioselective modification of a soluble protein. More specifically, the present invention provides a compound having an affinity substance to a soluble protein, a cleavable portion, and a reactive group represented by the following Formula (I): A-L-B-R (I) wherein A is an affinity substance to a soluble protein; L is a cleavable linker which is a divalent group comprising a cleavable portion; B is (a) a divalent group comprising a bioorthogonal functional group or (b) a divalent group comprising no bioorthogonal functional group; and R is a reactive group to the soluble protein; or a salt thereof.

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