MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202617071639 A) filed by The University Of North Carolina At on June 09, 2026, for Compositions And Methods Relating To Antiviral Therapeutics.
Inventors include Lai, Samuel; Zhao, Jingyu; Fritz, Marshall; Shen, Limei; and Olson, Lucas Number.
The application for the patent was published on July 10, 2026, under issue no. 28/2026.
Abstract: Disclosed herein are formulations for use in enhancing the transduction efficiency of lentiviral vector (LV) particles against different target cells. For example, described herein are formulations for use in enhancing transduction of a paramyxovirus pseudotyped lentivirus vector particle into a target cell that may include a cell penetrating peptide (CPP) comprising at least one of: vectofusion-1 or LAH4-C; and a poloxamer 407, wherein a concentration of the poloxamer 407 is in greater than the concentration of the CPP. Also described herein are methods of using these formulations to enhance transduction of LV particles, including in particular in vivo transduction.
Disclaimer: Curated by HT Syndication.
