MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202617077231 A) filed by Theras, Inc.; Leidos Biomedical Research, Inc.; and Lawrence Livermore National Security, LLC on June 23, 2026, for Compositions And Methods For Inhibition Of Ras.
Inventors include Zhang, Zuhui; Wang, Bin; Xu, Rui; Wallace, Eli; Turner, David Michael; Maciag, Anna Elzbieta; Simanshu, Dhirendra Kumar; Chan, Albert Hay Wah; Liao, Tao; Yang, Yue; Pei, Jun; and Lightstone, Felice.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: Provided herein are compounds, or salts, esters, tautomers, prodrugs, zwitterionic forms, or stereoisomers thereof, as well as pharmaceutical compositions comprising the same. Also provided herein are methods of using the same in modulating (e.g., inhibiting) KRAS (e.g., KRAS having a Q61H, G12D, G12V, G12C, G12S, G12A, G12R, or G13D mutation or wild-type KRAS, including wild-type amplified KRAS) and treating diseases or disorders such as cancers in subjects in need thereof.
Disclaimer: Curated by HT Syndication.
