MUMBAI, India, June 26 -- Intellectual Property India has published a patent application (202641072274 A) filed by Vellore Institute Of Technology on June 10, 2026, for Chiral Carbon Dot-Based Sensing Platform For Protein Aggregate Discrimination.

Inventors include Pranav; Sukanta Kumar Tulo; and Aswathi Unni.

The application for the patent was published on June 19, 2026, under issue no. 25/2026.

Abstract: ABSTRACT CHIRAL CARBON DOT-BASED SENSING PLATFORM FOR PROTEIN AGGREGATE DISCRIMINATION A method (300) for discriminating protein aggregates comprises providing (302) enantiomeric chiral carbon dots comprising D-Cysteine carbon dots and L-Cysteine carbon dots. The method further comprises combining (304) the chiral carbon dots with protein aggregate samples comprising native protein aggregates and heavy metal-induced protein aggregates. The method further comprises recording (306) fluorescence emission spectra from the combined chiral carbon dots and protein aggregate samples. The method further comprises applying (314) machine learning models to the fluorescence emission spectra to classify and discriminate between the native protein aggregates and the heavy metal-induced protein aggregates.

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