MUMBAI, India, June 19 -- Intellectual Property India has published a patent application (202411095681 A) filed by Indian Council Of Medical Research on December 04, 2024, for Chimeric Multi-Stage Vaccines For Preventing Plasmodium Falciparum And Plasmodium Vivax Infections And Their Community Transmissions.
Inventors include Dr. Singh, Subhash; Dr. Singh, Susheel Kumar; Dr. Singh, Vandana; and Dr. Pati, Sanghamitra.
The application for the patent was published on June 05, 2026, under issue no. 23/2026.
Abstract: The present disclosure relates to designing of chimeric recombinant vaccine constructs for eliciting protective immunity against Plasmodium falciparum and Plasmodium vivax. The vaccine constructs of the present disclosure comprise of homologs of full-length Circumsporozoite proteins fused with transmission blocking antigens for targeting P. falciparum and P. vivax thus providing protection against both human infections as well as reducing their community transmissions. Also, the present disclosure relates to development of recombinant chimeric multi-stage malaria vaccines for targeting P. falciparum and P. vivax that require safer adjuvants, such as alum, for formulation. This could streamline manufacturing processes and reduce costs, making the vaccines more accessible, especially in resource-limited settings.
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