MUMBAI, India, July 31 -- Intellectual Property India has published a patent application (202647088202 A) filed by Jiangxi Kvvit Pharmaceutical Co. , Ltd. on July 20, 2026, for Biphenyl Compound, Preparation Method Therefor, And Intermediate, Pharmaceutical Composition And Use Thereof.

Inventors include Yan, Shousheng; He, Honghong; Guan, Xitao; and Chen, Shuoji.

The application for the patent was published on July 24, 2026, under issue no. 30/2026.

Abstract: Disclosed in the present invention are a biphenyl compound, a preparation method therefor, and an intermediate, a pharmaceutical composition and the use thereof. Specifically provided is a compound as shown in formula I or a pharmaceutically acceptable salt thereof. The compound has good activity and selectivity on a retinoic acid receptor ? agonist, almost has no agonistic activity on retinoic acid receptors a and/or ß, and is thus beneficial to reducing systemic side effects. Preferably, the compound has moderately partial agonistic activity, has low skin irritation and few adverse reactions while maintaining its efficacy, and thus has good safety and compliance, such that the problems generally present in existing RAR compounds are effectively solved, and the compound can be used for treating and preventing diseases related to retinoic acid receptor ?.

Disclaimer: Curated by HT Syndication.