MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202641123519 A) filed by Indian Institute Of Technology Hyderabad on October 15, 2026, for Bioreactor Assembly And Method For Ex-Vivo Culture And Confocal Imaging Of Intact Corneal Tissue.
Inventors include Kousik Maparu; Samudra Bhaumik; Lopamudra Giri; and Saptarshi Majumdar.
The application for the patent was published on October 23, 2026, under issue no. 43/2026.
Abstract: ABSTRACT BIOREACTOR ASSEMBLY AND METHOD FOR EX-VIVO CULTURE AND CONFOCAL IMAGING OF INTACT CORNEAL TISSUE A bioreactor assembly (600) and method (1400) for ex-vivo culture and confocal optical imaging of an intact corneal tissue sample are disclosed. The assembly (600) comprises an outer transparent biocompatible chamber (106) defining a tissue-culture region, an inner tissue-culture assembly (200) removably received within the outer chamber (106), and a vertical positioning arrangement including one or more repositioning plates (400). The inner tissue-culture assembly (200) includes a tissue- loading region and a tightening member for retaining the intact corneal tissue sample. A transparent coverslip (108) is integrated with the outer chamber (106) to provide a confocal-compatible optical interface. The vertical positioning arrangement selectively positions the inner tissue-culture assembly (200) in a raised culture position and a lowered imaging position. In the lowered imaging position, the tissue sample is brought towards the coverslip (108) and within a working distance of a confocal microscope objective. (Fig. 6)
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