MUMBAI, India, June 24 -- Intellectual Property India has published a patent application (202411093236 A) filed by All India Institute Of Medical Sciences on November 28, 2024, for Bioengineered Small Extracellular Vesicles For Liver-Targeted Delivery And Method Of Preparation Thereof.
Inventors include Dr. Sujata Mohanty; and Meenakshi Mendiratta.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: The present disclosure relates to bioengineered small extracellular vesicles (sEVs) (100) for liver-targeted delivery. The bioengineered sEVs comprises small extracellular vesicles (sEVs) (102) derived from mesenchymal stem cells (MSC) (104); a hepatoprotective RNA (106) loaded into the small extracellular vesicles (sEVs); and a cationized pullulan (108) chemically conjugated to surface of the hepatoprotective RNA loaded small extracellular vesicles (sEVs). The present disclosure relates to a method of preparation of bioengineered small extracellular vesicles (sEVs) for liver-targeted delivery. FIG. 1
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