MUMBAI, India, Sept. 28 -- Intellectual Property India has published a patent application (202511012499 A) filed by Council Of Scientific And Industrial Research An Indian on February 13, 2025, for Benzodiazocine Compound As Antiviral Agent And Process For Preparation Thereof.
Inventors include Dumbala Srinivasa Reddy; Bokara Kiran Kumar; Nanduri Sathya Sai Saranya; Rahul Choudhury; Ganesh Routholla; Prathmesh Rajesh Supekar; Alna Kuriyickal Martin; and Renuga Devi Muruganandham.
The application for the patent was published on September 25, 2026, under issue no. 39/2026.
Abstract: This study presents the synthesis of novel Benzodiazocine analogues and their potential as potent antiviral agents. Benzodiazocines, featuring an eight-membered fused bicyclic core, adhere to Lipinski’s rule of five, ensuring drug-like properties. Structural modifications via Structure-Activity Relationship (SAR) enhanced their antiviral efficacy. In vitro assays, including cytotoxicity analysis and RT-qPCR-based studies, evaluated activity against SARS-CoV-2. Several analogues demonstrated promising antiviral potential, contributing to the ongoing pursuit of effective therapeutics against viral infections.
Disclaimer: Curated by HT Syndication.
