MUMBAI, India, June 30 -- Intellectual Property India has published a patent application (202641074807 A) filed by Mohan Babu University on June 17, 2026, for Assessment Of Dpph-Based Antioxidant Potential Of Aqueous Methanolic Extract Of Phyllanthus Niruri L..
Inventors include Dr. Janapati Pedda Yanadaiah; and Mr. H. Manikandan.
The application for the patent was published on June 26, 2026, under issue no. 26/2026.
Abstract: The present invention pertains to the evaluation of the antioxidant activity of an aqueous methanolic extract derived from Phyllanthus niruri L., a medicinal herb widely used in traditional Indian systems of medicine. The invention addresses the increasing demand for safe and effective natural antioxidants as alternatives to synthetic antioxidants, which are associated with toxic effects and limited biocompatibility. The whole plant material of Phyllanthus niruri was subjected to Soxhlet extraction using a methanol and water solvent system in the ratio of 70:30. The obtained extract was evaluated for its antioxidant potential using the DPPH (2,2-Diphenyl-1- picrylhydrazyl) free radical scavenging assay under in vitro conditions. Different concentrations of the extract were tested and compared with a standard antioxidant compound, namely Ascorbic acid. The results demonstrated significant dose-dependent free radical scavenging activity of the extract, indicating considerable antioxidant potential. The observed activity is attributed to the presence of naturally occurring phytoconstituents, including flavonoids, phenolic compounds, tannins, alkaloids, and related secondary metabolites capable of neutralising reactive oxygen species. The present invention provides a scientific basis for the development of plant-based antioxidant formulations using Phyllanthus niruri for potential applications in pharmaceutical, nutraceutical, cosmetic, and healthcare industries. The invention offers a natural, safe, economical, and biologically effective alternative to synthetic antioxidants for the management of oxidative stress-related conditions.
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