MUMBAI, India, June 30 -- Intellectual Property India has published a patent application (202617055869 A) filed by Avidity Biosciences, Inc. on May 01, 2026, for Antibody-Oligonucleotide Conjugate Compositions And Methods Of Inducing Dmd Exon 45 Skipping.
Inventors include Darimont, Beatrice Diana; Etxaniz Irigoien, Usue; Doppalapudi, Venkata Ramana; Cochran, Michael Caramian; Marks, Isaac; and Albin, Tyler.
The application for the patent was published on June 26, 2026, under issue no. 26/2026.
Abstract: Disclosed herein are binding moiety (e.g., antibody)- oligonucleotide (e.g., PMO) conjugates and pharmaceutical compositions that induce an alteration in an incorrectly spliced dystrophin mRNA transcript to induce DMD exon 45 skipping. Also described herein include methods for treating muscle dystrophy including Duchenne muscular dystrophy that comprises administering such conjugates or a pharmaceutical composition that induces alteration in an incorrectly spliced dystrophin mRNA transcript to induce DMD exon 45 skipping.
Disclaimer: Curated by HT Syndication.
