MUMBAI, India, Aug. 12 -- Intellectual Property India has published a patent application (202617053752 A) filed by Sixpeaks Bio AG on April 28, 2026, for Antibodies Targeting Actriia And Actriib.
Inventors include Kunz, Christian; Wiederkehr, Amlie; Wellinger, Lisa; Lain, Anne-Laure; Radke, Emily; Stein, Caitlin; and Sivasubramanian, Arvind.
The application for the patent was published on August 07, 2026, under issue no. 32/2026.
Abstract: The present disclosure relates to antibodies and antibody fragments that are specific for ActRIIA and ActRIIB. The antibodies are improved versions of bimagrumab. Antibodies of the present invention have an improved affinity against ActRIIA, translating into improved in vitro potency and efficacy, an improved PK and PD profile and a higher stability making the antibodies suitable for s.c. administration. Optionally they carry Fc modifications making the antibodies safe for prolonged treatments.
Disclaimer: Curated by HT Syndication.
