MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202641108398 A) filed by Dr. V. Asha Ranjani on September 09, 2026, for An Ultrasound-Assisted Acid Hydrolysis Method For Producing Bioactive Lotus Nanoparticles With Enhanced Antioxidant Properties.
Inventors include Dr. V. Asha Ranjani; Dr. V. Santhisree; Dr. Pasham Uma; Mrs. Asiya Shaik; Dr Dasari Nirmala; Mrs. Gayatri Devi; Dr R V Valli Kumari; Dr. Mohd Afroz; Dr. Sridhar Siddiraju; and Dr. Sudhakar. Muvvala.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: The present invention relates to a process for the preparation of bioactive nanoparticles from lotus (Nelumbo nucifera) petals employing a combination of acid hydrolysis and ultrasonicassisted treatment. The process comprises collecting and pre-treating fresh lotus petals by washing, shade-drying, and grinding the same into a fine powder, followed by extraction using a hydroalcoholic solvent system under controlled heating to obtain a crude extract rich in bioactive phytoconstituents such as flavonoids, phenolics, and alkaloids. The crude extract is subjected to acid hydrolysis using a mineral acid catalyst, and the hydrolysed extract is thereafter treated with ultrasonic irradiation within a defined frequency range under temperature-controlled conditions to induce acoustic cavitation and promote nanoparticle nucleation and growth. The resultant nanoparticle suspension is neutralized, and the nanoparticles are separated by centrifugation, washed, and dried to obtain a stable nanoparticulate powder. The nanoparticles so obtained are predominantly spherical in morphology, exhibit a particle size ranging from approximately 40 to 120 nanometres, and demonstrate significant concentration-dependent antioxidant activity, as confirmed by ultraviolet-visible spectroscopy, Fourier transform infrared spectroscopy, scanning electron microscopy, and antioxidant assays. The present invention provides a simple, eco-friendly, cost-effective, and scalable process for producing bioactive nanoparticles suitable for pharmaceutical, nutraceutical, and cosmeceutical applications.
Disclaimer: Curated by HT Syndication.
