MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202611089929 A) filed by Dr. Vaibhav Saran; Dr. Vijay Tripathi; Dr. Shubham Yadav; and Ms. Pallavi Kumari on July 23, 2026, for An Integrated Next-Generation Sequencing System For Contamination-Corrected Microbial Forensic Attribution And Method Thereof.
Inventors include Dr. Vaibhav Saran; Dr. Vijay Tripathi; Dr. Shubham Yadav; Ms. Pallavi Kumari; Ms. Sukriti Agrawal; Ms. Madhura Kurve; Ms. Kavita Sahu; and Dr. Rajeev Kumar.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: [096] The present invention discloses an integrated next-generation sequencing system for microbial forensic attribution. An evidence collection assembly acquires an evidence sample and a synchronized field control under a common machine-readable identifier while recording environmental exposure. Evidence, field-control and reagent-control nucleic acids are converted into distinguishably indexed libraries and sequenced. A processing unit derives a contamination transfer matrix from control read sets, corrects microbial features of the evidence read set, normalizes the corrected features according to an environmental exposure index, and generates a multi- layer microbial forensic signature comprising taxonomic and strain-discriminating features. Mixed signatures are resolved into contributor components and compared with selected reference signatures to generate a calibrated association or exclusion output with uncertainty and quality-gate status. An evidence-package generator cryptographically binds the sample identifier, sequence data, processing parameters, reference version and output, thereby reducing contamination-induced false association, environment-induced false exclusion and post-analysis data alteration. Accompanied Drawing [FIGS. 1-6]
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