MUMBAI, India, June 19 -- Intellectual Property India has published a patent application (202411088291 A) filed by All India Institute Of Medical Sciences on November 14, 2024, for An Engineered Scfv-Car And Method For Preparation And Utility.
Inventors include Dr. Singh, Mayank; Gupta, Ashna; Dr. Dagar, Gunjan; Dr. Luthra, Kalpana; and Dr. Prasad, Chandra Prakash.
The application for the patent was published on June 05, 2026, under issue no. 23/2026.
Abstract: The present invention discloses a scFv-CAR generated from monoclonal antibody (9C4). The scFv-CAR is directed against the extra cellular domain of BCMA (b-cell maturation antigen). The chimeric antigen receptor (CAR) comprising a leader sequence (CD8), a scFv sequence, a hinge region (CD8 alpha chain), a transmembrane domain (CD28), a co-stimulatory domain (4-1BB), an intracellular signalling domain (CD3 Zeta) and optionally an EGFP for directing against the extra cellular domain of BCMA (b-cell maturation antigen), a method for its preparation and its utility.
Disclaimer: Curated by HT Syndication.
