MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202641123058 A) filed by Indian Institute Of Technology Palakkad Iit Palakkad on October 14, 2026, for Amphiphilic Cationic Phenothiazine Schiff Base Compound And Method For Preparation And Antibacterial Application Thereof.
Inventors include Sushabhan Sadhukhan; Shabin N. Chathangad; Meenakshi K Kizhakkiniyil; Karthika Kannan; and Vishnu N. Vijayan.
The application for the patent was published on October 23, 2026, under issue no. 43/2026.
Abstract: The present invention provides an amphiphilic cationic phenothiazine Schiff base compound (100) having a phenothiazine ring system (102), a linear alkyl chain (104), a quaternary ammonium group (106), an aryl hydrazone moiety (108), and a counter anion (112). The linear alkyl chain (104) has 4 to 10 carbon atoms and connects the phenothiazine ring system (102) with the quaternary ammonium group (106). The quaternary ammonium group (106) is selected from N-butyl-N,N- dimethylammonium, trimethylammonium, triethylammonium, and 4-methylmorpholin-4-ium groups. The aryl group (110) has a nitro-substituted phenyl structure. A lead compound (100) has a pentane-1,5-diyl chain, an N-butyl-N,N-dimethylammonium group, a 2,4-dinitrophenyl hydrazone moiety (108), and bromide as the counter anion (112). A method for preparation includes sequential N-alkylation, Vilsmeier–Haack formylation, quaternization, and condensation with an arylhydrazine.
Disclaimer: Curated by HT Syndication.
