MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202527105087 A) filed by Shenzhen Magicrna Biotechnology Co. on October 30, 2025, for Amino Lipid, And Lipid Nanoparticles And Use Thereof.
Inventors include Fang, Wanyin; Qin, Haoyong; Xu, Yan; and Wu, Qixin Number.
The application for the patent was published on July 10, 2026, under issue no. 28/2026.
Abstract: The present invention provides an amino lipid, and lipid nanoparticles (LNPs) and a use thereof, the amino lipid having a structure represented by general formula (I), or an isomer, pharmaceutically acceptable salt, prodrug or solvate of the amino lipid. The present invention further provides LNPs containing the amino lipid. According to the present invention, the amino lipid having a structure represented by general formula (I) is used as an ionizable lipid compound, and the LNPs are obtained by means of self-assembly of the ionizable lipid compound, a steroid, a neutral lipid, and a polymer-bonded lipid. The LNPs can further improve the translation expression level of a nucleic acid load in cells, improve the effect of a nucleic acid-LNP preparation, and enable the nucleic acid-LNP preparation to provide a theoretical basis for personalized treatment.
Disclaimer: Curated by HT Syndication.
