MUMBAI, India, July 7 -- Intellectual Property India has published a patent application (202641058115 A) filed by Saveetha Institute Of Medical And Technical Sciences on May 07, 2026, for Allicin-Enriched Antimicrobial Gel For Topical Application.
Inventors include Dr. G. Bhuvaneshwari; Kavikumar K; and Deepak Nallaswamy Veeraiyan.
The application for the patent was published on July 03, 2026, under issue no. 27/2026.
Abstract: Abstract: The present invention relates to a topically applicable allicin-based antibacterial gel formulation exhibiting enhanced inhibitory activity against Gram-positive bacteria, particularly methicillinresistant Staphylococcus aureus (MRSA). The composition includes a stabilizing agent, a hydrophilic gel base, and controlled-release enhancers that preserve allicin's active form. The formulation comprises a stabilized allicin extract incorporated into a biocompatible polymeric gel matrix capable of maintaining allicin stability, bioavailability, and sustained release. The resulting gel provides sustained antimicrobial release, enhanced penetration, and significant improvement in killing efficiency compared to standard allicin solutions. The invention provides improved antibacterial efficacy through optimized concentration ranges, pH control, and synergistic additives that prevent allicin degradation. The gel demonstrates rapid bactericidal activity, reduced MIC values, and superior stability compared to conventional garlic extracts. This invention is applicable for treating skin infections, wound care, and other clinical conditions associated with MRSA contamination Abstract: The present invention relates to a topically applicable allicin-based antibacterial gel formulation exhibiting enhanced inhibitory activity against Gram-positive bacteria, particularly methicillinresistant Staphylococcus aureus (MRSA). The composition includes a stabilizing agent, a hydrophilic gel base, and controlled-release enhancers that preserve allicin's active form. The formulation comprises a stabilized allicin extract incorporated into a biocompatible polymeric gel matrix capable of maintaining allicin stability, bioavailability, and sustained release. The resulting gel provides sustained antimicrobial release, enhanced penetration, and significant improvement in killing efficiency compared to standard allicin solutions. The invention provides improved antibacterial efficacy through optimized concentration ranges, pH control, and synergistic additives that prevent allicin degradation. The gel demonstrates rapid bactericidal activity, reduced MIC values, and superior stability compared to conventional garlic extracts. This invention is applicable for treating skin infections, wound care, and other clinical conditions associated with MRSA contamination Abstract: The present invention relates to a topically applicable allicin-based antibacterial gel formulation exhibiting enhanced inhibitory activity against Gram-positive bacteria, particularly methicillinresistant Staphylococcus aureus (MRSA). The composition includes a stabilizing agent, a hydrophilic gel base, and controlled-release enhancers that preserve allicin's active form. The formulation comprises a stabilized allicin extract incorporated into a biocompatible polymeric gel matrix capable of maintaining allicin stability, bioavailability, and sustained release. The resulting gel provides sustained antimicrobial release, enhanced penetration, and significant improvement in killing efficiency compared to standard allicin solutions. The invention provides improved antibacterial efficacy through optimized concentration ranges, pH control, and synergistic additives that prevent allicin degradation. The gel demonstrates rapid bactericidal activity, reduced MIC values, and superior stability compared to conventional garlic extracts. This invention is applicable for treating skin infections, wound care, and other clinical conditions associated with MRSA contamination In another embodiment, the invention provides methods for preparing the stabilized allicin gel. The process involves controlled garlic extraction under low-temperature, oxygen-reduced conditions to maximize allicin yield, followed by immediate stabilization and incorporation into the gel matrix. This minimizes allicin decomposition and ensures uniform dispersion throughout the formulation. The preparation method may also include optional steps such as filtration, pH adjustment, and incorporation of excipients that optimize texture, shelf- life, and clinical usability. The invention also covers therapeutic applications of the gel formulation. When applied to infected skin, wounds, bums, or post-surgical sites, the gel provides localized antimicrobial activity without causing irritation or toxicity. Due to its natural origin and biocompatibility, the allicin gel represents a safer alternative to synthetic antibiotics and reduces the risk of adverse reactions . Additionally, the gel may prevent or disrupt MRSA biofilms, further contributing to its clinical utility.
Disclaimer: Curated by HT Syndication.
