MUMBAI, India, July 7 -- Intellectual Property India has published a patent application (202641058758 A) filed by Bvrit Hyderabad College Of Engineering For Women; Dr. Anna Tanuja Safala Bodapati; Dr. Bijaya Ketan Sahoo; Dr. Ragaiahgari Srinivas Reddy; Dr. Kandikonda Lavanya; and Shravya Rao Madku on May 08, 2026, for A System And Method For Drug Biomolecular Interaction Analysis.
Inventors include Dr Anna Tanuja Safala Bodapati; Dr. Bijaya Ketan Sahoo; Dr. Ragaiahgari Srinivas Reddy; Dr. Kandikonda Lavanya; and Shravya Rao Madku.
The application for the patent was published on July 03, 2026, under issue no. 27/2026.
Abstract: Abstract: The present invention relates to a method for analyzing drug-biomolecular interactions, particularly the binding behavior of Esomeprazole with Human Serum Albumin. I'he invention provides a combined spectroscopic computational approach to evaluate binding parameters, interaction forces, thermodynamic characteristics of drug-protein complexes. and and The method determines binding constants, free energy changes, enthalpy, entropy contributions to assess the stability and nature of interaction, invention further identifies the preferential binding site of the drug on the protein and analyzes structural modifications induced in the protein upon binding. Computational techniques, including molecular docking and interaction mapping, are used to validate experimental findings and identify key residues involved in binding. and The The proposed method enables accurate prediction of drug binding affinity, interaction energetics, and structural impact on biomolecules, thereby providing valuable insights for drug design, pharmacokinetics, and therapeutic optimization. The invention is useful in pharmaceutical research, drug discovery, and biomolecular interaction studies
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