MUMBAI, India, July 24 -- Intellectual Property India has published a patent application (202611067618 A) filed by Dr. Ashwani Kumar; Mr. Rajinder Singh; Dr. Rahul; Dr. Vinod Katoch; Dr. Ankush Kumar; Dr. Bhawana Sharma; and Dr. Divaker Shukla on May 29, 2026, for A Synergistic Herbal Aqueous Composition For Oral Hygiene Derived From Himalayan Flora.

Inventors include Dr. Ashwani Kumar; Mr. Rajinder Singh; Dr. Rahul; Dr. Vinod Katoch; Dr. Ankush Kumar; Dr. Bhawana Sharma; and Dr. Divaker Shukla.

The application for the patent was published on July 17, 2026, under issue no. 29/2026.

Abstract: The present invention discloses a synergistic herbal aqueous composition for oral hygiene derived from Himalayan flora, comprising standardized aqueous extracts of Juglans regia (30 to 40 percent), Vitex negundo (20 to 25 percent), Justicia adhatoda (15 to 20 percent), and Zanthoxylum armatum (20 to 25 percent). The composition exploits pharmacological synergism among phenolics, flavonoids, alkaloids, and alkylamides to deliver enhanced antimicrobial efficacy against biofilm-forming oral pathogens including Streptococcus mutans, with minimum inhibitory concentration values at least 3-fold lower than individual extracts and fractional inhibitory concentration index of 0.35 confirming true synergism. The formulation concurrently provides anti-inflammatory activity through cyclooxygenase-2 and matrix metalloproteinase inhibition, and sustained analgesic effect through TRPA1 and TRPV1 receptor modulation

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