MUMBAI, India, Aug. 24 -- Intellectual Property India has published a patent application (202511010744 A) filed by Indian Council Of Agricultural Research Icar on February 08, 2025, for A Recombinant Protein Antigen For Differentiating Lsd Virus Infected And Vaccinated Animals, Recombinant Dna Molecules Encoding Said Recombinant Protein Antigens And Methods Thereof.
Inventors include Naveen Kumar; Alka Nokhwal; Yogesh Chander; Assim Verma; and Thachamvally Riyesh.
The application for the patent was published on August 21, 2026, under issue no. 34/2026.
Abstract: The invention relates to a recombinant DNA molecule to differentiate lumpy skin disease (LSD) infected and vaccinated animals. The recombinant DNA molecule comprises ORF154 of lumpy skin disease virus (LSDV) and encodes a protein that reacts with sera of infected animals and not with the vaccinated or naïve animals. The invention also provides antigens for differentiating lumpy skin disease (LSD) infected and vaccinated animals. In addition, the present invention also relates to method of developing ORF154-based ELISA as a reliable serological diagnostic tool for LSDV surveillance and disease control programs. The assay exhibits high sensitivity (96.125%) and specificity (95.77%), effectively distinguishing infected from vaccinated cattle.
Disclaimer: Curated by HT Syndication.
