MUMBAI, India, July 31 -- Intellectual Property India has published a patent application (202411100693 A) filed by Council Of Scientific And Industrial Research, An Indian Registered Body Incorporated Under The Regn. Of Soc. Act Act Xxi Of on December 18, 2024, for A Process For The Preparation Of Lenalidomide And Intermediates Thereof.

Inventors include Amol Babasaheb Gade; Ahemad Mahebubsab Pathan; Raj Sunil Wandre; and Zabeer Ahmed.

The application for the patent was published on July 24, 2026, under issue no. 30/2026.

Abstract: The present invention introduces an environmentally friendly and cost-effective method for synthesizing 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6- dione (III), commonly known as lenalidomide. This disclosure also includes methods for preparing lenalidomide intermediates I and II. The process avoids hazardous solvents and simplifies post-processing, thereby addressing environmental, health, and safety concerns while reducing production costs.

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