MUMBAI, India, Nov. 2 -- Intellectual Property India has published a patent application (202611015389 A) filed by East Ocyon Bio Private Limited on February 12, 2026, for A Process For Expanding Natural Killer (nk) Cells.
Inventors include Dinesh Kundu; Renu Kundu; Prasad Krishnamurthy; Apratim Tripathi; Priyanka Chaudhary; and Rohit Rajput.
The application for the patent was published on October 30, 2026, under issue no. 44/2026.
Abstract: The present disclosure relates to a process for expanding NK cells. The process involves culturing NK cells in an NK cell culturing medium with combinations of IL-2, IL-12, IL-15 and IL-18 for 4-6 days; replacing the NK cell culturing medium on day 4, 5, or 6, with NK cell expansion media with combinations of IL-2, IL-15 and IL- 18 (without IL-12), and culturing for 4-5 days; and replacing spent NK cell expansion medium on day 8, 9, 10, or 11, with fresh 10 NK cell expansion medium with IL- 2, IL-15, and IL-18 (without IL-12), and continuing culturing of the NK cells up to 14-25 days to obtain expanded NK cells. The process provides for 200-1000-fold expansion of NK cells. The process is feeder-free and has less regulatory risks compared to feeder-based methods. 15 FIGURE 1(a)
Disclaimer: Curated by HT Syndication.
