MUMBAI, India, July 7 -- Intellectual Property India has published a patent application (202617070091 A) filed by Intervet International B. V. on June 04, 2026, for A Process For Chiral Resolution Oftrans-2,2-Dichloro-3-(3-Chloro-4- Fluorophenyl) Cyclopropane-1-Carboxylic Acid.
Inventors include Chassaing, Christophe, Pierre, Alain; and Seupel, Raina Pctep Application No.
The application for the patent was published on July 03, 2026, under issue no. 27/2026.
Abstract: The present invention provides a method for chiral resolution of (trans)-2,2-dichloro-3-(3-chloro-4- fluorophenyl)cyclopropane-1- carboxylic acid. The method comprises the steps of: (a) treating (trans)-2,2- dichloro-3-(3-chloro-4-fluorophenyl)cyclopropane-1- carboxylic acid with a chiral base selected from the list consisting of quinine, (R)-1-cyclohexylethan-1-amine, (S)-1-cyclohexylethan- 1-amine and (L)-leucinamide in an organic solvent to form a suspension, (b) isolating a diastereoisomeric salt of the desired enantiomer and the chiral base from the suspension, and (c) optionally, treating the isolated diastereoisomeric salt with an acid to obtain the desired enantiomer of 2,2-dichloro-3-(3-chloro-4-fluorophenyl)cyclopropane-1- carboxylic acid.
Disclaimer: Curated by HT Syndication.
