MUMBAI, India, June 30 -- Intellectual Property India has published a patent application (202621056841 A) filed by Dr Ashwini A. Zanke; Prof. Leena P. Joge; Prof. Vikas N. Ghait; Prof. Ananta G. Titare; Dr. Ankush Maskar; Priyanka Patil; Pranjali Parate; Jagadish Wani; Dr. Vaishali Vaidya; and Dr. Suman Gehlot on May 05, 2026, for A Polyherbal Niosomal Topical Composition For The Treatment Of Atopic Dermatitis.
Inventors include Dr Ashwini A. Zanke; Prof. Leena P. Joge; Prof. Vikas N. Ghait; Prof. Ananta G. Titare; Dr. Ankush Maskar; Priyanka Patil; Pranjali Parate; Jagadish Wani; Dr. Vaishali Vaidya; and Dr. Suman Gehlot.
The application for the patent was published on June 26, 2026, under issue no. 26/2026.
Abstract: The present invention provides a polyherbal niosomal topical gel composition for the treatment of atopic dermatitis, comprising hydroalcoholic extracts of Curcuma longa, Calendula officinalis and Lawsonia inermis together with Rosmarinus officinalis essential oil, co-encapsulated in non-ionic surfactant vesicles formed of Span 60 and cholesterol by the thin-film hydration technique, and dispersed in a Carbopol 934 hydrogel matrix containing propylene glycol, glycerin, parabens and triethanolamine. The niosomes show vesicle size of 180-250 nm, polydispersity index of 0.25-0.35, zeta potential of -25 to -32 mV and entrapment efficiency of 75- 88%. The resulting gel of pH 5.5-6.5 exhibits sustained release over 24 hours, enhanced ex vivo permeation, significant anti-inflammatory and antimicrobial activity against S. aureus and C. albicans, and excellent stability.
Disclaimer: Curated by HT Syndication.
