MUMBAI, India, Sept. 28 -- Intellectual Property India has published a patent application (202641111013 A) filed by Dr B Nagaraj; Lavanya Meiyammai P; Sathana E; Mathina S; Vishnu K; Priyadharshini R; and Anbuselvan A on September 16, 2026, for A Novel Rapid And Cost Effective Method For Extraction Of Deoxyribonucleic Acid (dna) Using Functionalized Magnetic Nanoparticles.
Inventors include Lavanya Meiyammai P; Sathana E; Mathina S; Vishnu K; Priyadharshini R; and Anbuselvan A.
The application for the patent was published on September 25, 2026, under issue no. 39/2026.
Abstract: The present invention discloses a novel rapid and cost-effective method for extraction of deoxyribonucleic acid (DNA) using functionalized magnetic nanoparticles. The invention belongs to the fields of biotechnology, nanotechnology, and molecular diagnostics, and provides an efficient technique for isolating high-quality DNA from various biological samples. The proposed method utilizes surface-functionalized magnetic nanoparticles designed to selectively bind DNA molecules through electrostatic and affinity-based interactions. Initially, biological samples such as blood, saliva, plant tissues, microbial cultures, or other biological materials are treated with lysis buffers to release intracellular DNA. Functionalized magnetic nanoparticles are then introduced into the sample mixture to facilitate selective DNA adsorption onto the nanoparticle surface. Following DNA binding, an external magnetic field is applied to rapidly separate DNA-bound nanoparticles from contaminants and unwanted cellular debris. Washing steps are performed to remove residual impurities, and purified DNA is subsequently eluted using an appropriate buffer solution. The proposed method eliminates multiple centrifugation steps involved in conventional extraction procedures, thereby reducing processing time, reagent consumption, and operational complexity. The invention offers advantages including improved DNA purity, higher extraction efficiency, reduced sample loss, and cost-effective operation. Furthermore, the method can be adapted for automation and large-scale applications. The purified DNA obtained through this process is suitable for downstream applications such as polymerase chain reaction (PCR), sequencing, forensic analysis, disease diagnostics, pathogen detection, and biotechnology research. Therefore, the invention provides a simple, scalable, and economically feasible alternative for rapid DNA extraction.
Disclaimer: Curated by HT Syndication.
