MUMBAI, India, July 7 -- Intellectual Property India has published a patent application (202641077911 A) filed by Svvnsm Lakshmi; Ramadevi Korni; and Vishnu Institute Of Pharmaceutical Education And Research on June 24, 2026, for A Novel Hydrotropic Solid Dispersion Composition Of Olanzapine For Enhanced Aqueous Solubility, Dissolution And Oral Bioavailability.
Inventors include Svvnsm Lakshmi; Ramadevi Korni; and Vishnu Institute Of Pharmaceutical.
The application for the patent was published on July 03, 2026, under issue no. 27/2026.
Abstract: The present invention relates to a hydrotropic solid dispersion formulation of olanzapine for improving aqueous solubility and dissolution behavior. Hydrotropic agents such as sodium benzoate and caffeine were investigated individually and in combination. Solid dispersions were prepared and evaluated using dissolution studies, FTIR and DSC analyses. The developed formulation demonstrated improved solubility and dissolution characteristics, suggesting its potential application for enhancing oral bioavailability of poorly water-soluble drugs.
Disclaimer: Curated by HT Syndication.
