MUMBAI, India, Aug. 31 -- Intellectual Property India has published a patent application (202611047238 A) filed by Mangalayatan University, Aligarh; Dr. Arbab Husain; and Dr. Afreen Khanam on April 13, 2026, for A Novel C-Phycocyanin (c-Pc)-Based Composition And System For Quorum Sensing Inhibition And Biofilm Disruption In Pathogenic Microorganisms.
Inventors include Dr. Arbab Husain; Dr. Afreen Khanam; Er. Ghayyum Husain; Mr. Shirjeel Ahmad Siddiqui; Dr. Zeeshan Rafi; Dr. Suhail Ahmad; Dr. Gyanendra Tripathi; and Dr. Mohammad Amir.
The application for the patent was published on August 28, 2026, under issue no. 35/2026.
Abstract: The present invention relates to a system (100) for quorum sensing inhibition and biofilm disruption in pathogenic microorganisms using a C-phycocyanin-based composition. The system (100) comprises a C-phycocyanin composition unit (1) configured to provide a bioactive composition, a microbial exposure unit (2) configured to expose pathogenic microorganisms thereto, a quorum sensing inhibition unit (3) configured to suppress microbial communication pathways, a biofilm disruption unit (4) configured to inhibit and/or disrupt biofilm formation, an in-silico validation unit (5) configured to determine binding affinity of C-phycocyanin with quorum sensing regulatory proteins, an in-vitro validation unit (6) configured to perform biological assays for quorum sensing inhibition and antibiofilm activity, and an analysis unit (7) configured to correlate computational and experimental results. The system provides a natural, biocompatible, and eco-friendly approach for reducing virulence and biofilm-associated infections without primarily targeting microbial viability, thereby lowering the possibility of antimicrobial resistance development.
Disclaimer: Curated by HT Syndication.
