MUMBAI, India, Oct. 12 -- Intellectual Property India has published a patent application (202641118221 A) filed by Dr. P. Laxmi Madhuri Pi; Ms. V. Harika; Mr. Naga Mallesh; Mrs. D. Sushma; Dr. B. Karuna Devi; Dr. Ch. Sowjanya; Mrs. Dodda Mahalaxmi; Mrs. Yalamanchili Praharsha; Ms. Udayabhanu Bommaraju; and Dr. S. Ravindra Babu on October 02, 2026, for A Nano-Engineered Ph-Responsive Hydrogel Wound Dressing Incorporating Cabbage-Derived Bioactives And Chitosan Nanoparticles.

Inventors include Dr. P. Laxmi Madhuri Pi; Ms. V. Harika; Mr. Naga Mallesh; Mrs. D. Sushma; Dr. B. Karuna Devi; Dr. Ch. Sowjanya; Mrs. Dodda Mahalaxmi; Mrs. Yalamanchili Praharsha; Ms. Udayabhanu Bommaraju; and Dr. S. Ravindra Babu.

The application for the patent was published on October 09, 2026, under issue no. 41/2026.

Abstract: The present invention provides a nano-engineered pH-responsive hydrogel wound dressing integrating cabbage-derived bioactive delivery and visual monitoring of the wound microenvironment in a single dressing structure. The dressing comprises cabbage-derived bioactive extract incorporated into chitosan nanoparticles, wherein the nanoparticles are dispersed within a hydrogel matrix comprising polyvinyl alcohol and sodium alginate. The nano-engineered pH-responsive hydrogel wound-dressing formulation, comprising, per 25 mL of formulation, 2 g (8% w/v) of cabbage-derived extract, 0.30 g (1.2% w/v) of chitosan, forming chitosan nanoparticles incorporating the cabbage-derived extract, 1.5 g (6% w/v) of polyvinyl alcohol as a film-forming polymer, 0.4 g (1.6% w/v) of sodium alginate as a hydrogel matrix component, 0.6 g (2.4% w/v) of glycerol as a plasticizer; and f) 0.2–0.3 mL of anthocyanin extract as a pH-responsive indicator. The formulation is cast and dried to form a flexible hydrogel film. The prepared dressing exhibits thickness uniformity, mechanical strength, folding endurance and appreciable swelling capacity. The anthocyanin indicator exhibits a visually detectable colour response under different pH conditions. The integrated dressing thereby combines nanoparticle-mediated bioactive delivery, hydrogel-based moisture management and pH-responsive visual sensing in a single wound-care platform.

Disclaimer: Curated by HT Syndication.