MUMBAI, India, Aug. 31 -- Intellectual Property India has published a patent application (202641100965 A) filed by Therallen Pharma Private Limited on August 20, 2026, for A Multiparticulate Pharmaceutical Composition Comprising Xanomeline And Trospium Chloride And Process For Preparing Thereof.
Inventors include Ramireddy Vijayabhaskara Reddy; Vatti Sumanth Reddy; Dr. Padala Narayana Raju; Bobba Srinivas; and Dama Viswanadham.
The application for the patent was published on August 28, 2026, under issue no. 35/2026.
Abstract: The present invention relates to a multiparticulate pharmaceutical composition comprising Xanomeline and Trospium chloride. The composition comprises a plurality of discrete pellet or micro pellet units, wherein each pellet or micro pellet unit comprises a common core, a first drug-containing region comprising Xanomeline or a pharmaceutically acceptable salt thereof, at least one barrier region and a second drug-containing region comprising Trospium chloride. In an embodiment, the common core comprises microcrystalline cellulose and Xanomeline is provided as Xanomeline tartrate. The Xanomeline containing region may comprise microcrystalline cellulose, ascorbic acid and polyvinylpyrrolidone, while the Trospium containing region may comprise microcrystalline cellulose, lactose monohydrate and polyvinylpyrrolidone. The invention further provides processes involving sequential fluid-bed drug layering and coating and an extrusion-spheronization embodiment. The pellet or micro pellet units may be filled into capsules or compressed into MUPS tablets.
Disclaimer: Curated by HT Syndication.
