MUMBAI, India, Oct. 12 -- Intellectual Property India has published a patent application (202641118219 A) filed by Dr. G. Selvi on October 02, 2026, for A Multi-Layered Polyherbal Mucoadhesive Buccal Patch Delivery System And A Process For The Preparation Thereof.
Inventors include Dr. G. Selvi; Dr. T. Purushoth Prabhu; Ms. Rubykaa. M; Ms. Priyadharshini. J; Ms. Padmashri. R. U; Ms. Roshiga Dhanalakshmi. S; Dr J. Gomathi; Dr. W. Clement Atlee; Dr. S. Daniel Sundar Singh; and Dr. Malarkodi Velraj.
The application for the patent was published on October 09, 2026, under issue no. 41/2026.
Abstract: The present invention provides a multi-layered mucoadhesive buccal patch for the modified-release, unidirectional transmucosal delivery of Berberine, Mangiferin, and Epigallocatechin gallate (EGCG). Prepared via sequential solvent-casting, the delivery system comprises 1–40% (w/w) active ingredients integrated into a mucoadhesive matrix (HPMC K4M, Carbopol 934P, PVP K30, and a plasticizer), which is bonded to an impermeable backing layer (Ethyl cellulose and dibutyl phthalate) constituting the remaining 60–99% (w/w). The structurally intact patch circumvents hepatic first-pass metabolism, maintains a physiological surface pH (5.5– 7.5), and yields a controlled-release profile characterized by an initial dissolution lag phase followed by sustained transmucosal release peaking between 60 and 90 minutes.
Disclaimer: Curated by HT Syndication.
