MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202611089501 A) filed by Chitkara University on July 22, 2026, for A Modular Micro-Bioreactor System With Disposable Cartridge, Integrated Purification And Qc Modules.
Inventors include Dr. Sonia Dhiman; Dr. Shareen Singh; and Dr. Thakur Gurjeet Singh.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: The present invention a modular micro-bioreactor system (100) enables pharmacy-scale manufacture of biologics from a disposable sterile cartridge (200). A micro- bioreactor chamber (500) receives cell-free expression reagents (300) or engineered production cells (400), while a nutrient reservoir (600), thermal control assembly (2600), and inline sensors (900) maintain processing conditions. Product passes through a clarification module (2900), purification microcolumns (700), buffer exchange module (800), and closed split-stream sampling manifold (2200) to a quality control assay module (1100). A keyed aseptic manifold interface (1600), cartridge identity module (1700), and pre-use integrity test circuit (1800) prevent unauthorized or leaking cartridges from operating. A system controller (1300) actuates a microfluidic valve manifold (2000), compensates sensor drift using a reference-sensor microchannel (2500), and routes failed material to a quarantine chamber (2300). An electromechanical release-gate valve (2700) permits sterile filling only after quality limits and authorized release are satisfied, while a batch record module (2400) preserves traceable process evidence. (Accompanied Figure No. 1 to 4)
Disclaimer: Curated by HT Syndication.
