MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202611089500 A) filed by Chitkara University on July 22, 2026, for A Microfluidic Screening System With Cargo-Loading And Ranking Modules For Exosome Formulations.
Inventors include Dr. Sonia Dhiman; Dr. Shareen Singh; and Dr. Thakur Gurjeet Singh.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: The present invention a microfluidic screening system (100) is disclosed for parallel preparation, characterisation, in-vitro evaluation, and technical ranking of exosome formulations. The system comprises a microfluidic isolation module (200), a cargo-loading module (300) having parallelised loading chips (400), a ligand conjugation chamber (500), a readout module sensor (600), a cell uptake assay plate (700), a processor-implemented ranking module (800), and a combinatorial matrix controller (900). The isolation module (200) enriches extracellular vesicles from donor-cell-conditioned medium, while the cargo-loading module (300) introduces cargo under controlled loading energy and temperature. The readout module sensor (600) generates particle-size, yield, fluorescence, and cargo-retention data, and the cell uptake assay plate (700) generates uptake and viability data. The ranking module (800) produces a lane-specific score and communicates through a hardware control interface to adjust a physical formulation parameter only when predetermined quality thresholds are satisfied, thereby enabling traceable, closed-loop, sterile, and reproducible formulation screening without therapeutic administration. (Accompanied Figure No. 1 to 4)
Disclaimer: Curated by HT Syndication.
