MUMBAI, India, Sept. 28 -- Intellectual Property India has published a patent application (202521015309 A) filed by Rungta International Skills University; Rungta College Of Engineering & Technology; and Rungta College Of Pharmaceutical Sciences And Research on February 22, 2025, for A Method Of Preparation Of Extended-Release Osmotic Bilayer Drug Delivery System For Type 2 Diabetes.
Inventors include Mansee Nagdev; Karan Kumar Dharme; Aakash Gupta; Ayush Kumar Dewangan; Rahul Kumar Parwat; Ishwar Prasad Sah; Kamal Kant Sahu; Jitendra Sahu; and Chaitanya Gopal Malani.
The application for the patent was published on September 25, 2026, under issue no. 39/2026.
Abstract: A method of preparation of Extended-Release Osmotic Bilayer Drug Delivery System for Type 2 Diabetes. This invention describes an advanced extended-release osmotic bilayer drug delivery system designed to enhance the management of Type 2 diabetes mellitus. The system comprises a semi-permeable membrane, an osmotic push layer, and a drug-containing layer, ensuring sustained and controlled drug release through a laser-drilled orifice. Leveraging osmotic principles, the system facilitates precise and predictable drug delivery, independent of gastrointestinal pH or motility, maintaining consistent plasma drug levels over 12–24 hours. This approach improves therapeutic efficacy, minimizes dosing frequency, and enhances patient compliance while reducing the risk of side effects associated with fluctuating drug concentrations. The system’s customizable release kinetics enable patient-specific adaptations, addressing individual needs based on disease progression or comorbidities. With applications across various anti-diabetic agents and potential extension to other chronic therapies, this invention establishes a scalable and innovative platform for controlled-release pharmaceutical formulations, promoting improved clinical outcomes and treatment adherence.
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