MUMBAI, India, Aug. 10 -- Intellectual Property India has published a patent application (202411104310 A) filed by Lingaya'S Vidyapeeth on December 30, 2024, for A Method For Synthesis Of Mannich Derivative Using Indole Substituted Derivatives.
Inventors include Dr. Picheswar Gadde; Mr. Bhavik Kuchipudi; Mr. Rajling Gadde; Mr. Viraj Gadde; Dr. Chinnaiyan Ramasubramanian; Dr. Radhe Shyam; Dr. Seema Bushra; Dr. Samriti Mahajan; Dr. Rizwan Arif; Dr. Pranav Mishra; Dr. Javalkar Dinesh Kumar; Dr. Manoj K Malik; Ar. Aditi Arora; Dr. Mortha Chinna Rao; and Mr. Saurabh Kumar.
The application for the patent was published on July 31, 2026, under issue no. 31/2026.
Abstract: ABSTRACT A METHOD FOR SYNTHESIS OF MANNICH DERIVATIVE USING INDOLE SUBSTITUTED DERIVATIVES A method (100) for synthesis of Mannich derivative using Indole substituted derivatives. Further, the method comprising: Reacting indole substituted derivatives with formaldehyde and acetophenone derivatives through a condensation reaction. Further, monitoring the progress of the reaction using Thin Layer Chromatography (TLC) in a solvent system consisting of ethyl acetate and hexane in a 1:1 ratio. Further, Characterizing the synthesized product by Infrared (IR) spectroscopy, Ultraviolet-Visible (UV-Vis) spectroscopy, and Nuclear Magnetic Resonance (NMR) spectroscopy. Further, the synthesized Mannich derivatives exhibit sensing properties in various solvents including ethanol, methanol, acetic acid, dichloromethane, and dimethyl sulfoxide. FIG. 1
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