MUMBAI, India, June 24 -- Intellectual Property India has published a patent application (202617060946 A) filed by Merck Sharp & Dohme LLC on May 13, 2026, for A Cyclic Peptide For Trapping Interleukin-1 Beta.
Inventors include Cruz, Faben A.; Feng, Danqing; Guo, Yan; Hanisak, Jennifer; Hickey, Jennifer L.; Kalyani, Dipannita; Kekec, Ahmet; Li, Bing; Lo, Michael Man-Chu; Pissarnitski, Dmitri A.; Plummer, Christopher W.; Truong, Quang T.; and Colarusso, Stefania.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: Provided are compounds of the Formula (I), or their pharmaceutically acceptable salts, wherein X1, X2, X3, R1-R9, RA, RB, RD, A1, A2, and subscripts t and w are as herein described. Formula (I),(I). The compounds and their pharmaceutically acceptable salts can trap IL-1ß and are expected to have utility as therapeutic agents, for example, for treating cardiovascular disease and inflammatory disorders. The disclosure also provides pharmaceutical compositions which comprise the compounds disclosed herein or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cardiovascular disease and inflammatory disorders and for preparing pharmaceuticals for this purpose.
Disclaimer: Curated by HT Syndication.
