MUMBAI, India, Nov. 2 -- Intellectual Property India has published a patent application (202641125881 A) filed by Nitte Deemed To Be University; Dr Ashwini M; Ms Dhanya; Ms Manya C N; Ms Nagashree Umesh Achari; and Ms Varshitha R Shetty on October 22, 2026, for A Composition For An Oral Film For The Treatment Of Migraine And Preparation Method Thereof.
Inventors include Dr Ashwini M; Ms Dhanya; Ms Manya C N; Ms Nagashree Umesh Achari; and Ms Varshitha R Shetty.
The application for the patent was published on October 30, 2026, under issue no. 44/2026.
Abstract: Disclosed herein is a pharmaceutical composition (200) for oral film in the treatment of migraine, the composition (200) comprising lasmiditan (202) as active pharmaceutical ingredient (102), to provide therapeutic treatment of migraine attacks, hydroxypropyl methylcellulose (HPMC E15) (204) as film-forming polymer (104), to form a rapidly disintegrating oral film matrix, polyethylene glycol 4000 (PEG 4000) (206) as plasticizer (106), to impart flexibility, mechanical strength, and stability to the film, water (208) as solvent (108) to dissolve and uniformly disperse the formulation components during preparation of the melt-in-mouth film. The composition (200) further comprises a saliva-stimulating agents (210) to promote salivary secretion and reduce the disintegration time of the melt-in-mouth film to facilitate rapid release of lasmiditan (202). The composition (200) further comprises sweetening agents (212) to mask the inherent bitterness of lasmiditan (202) without adversely affecting film integrity and drug release.
Disclaimer: Curated by HT Syndication.
