MUMBAI, India, Aug. 10 -- Intellectual Property India has published a patent application (202647090444 A) filed by Polbionica Spolka Z Ograniczona on July 24, 2026, for A Bioprinted Liver Model, A Method For Manufacturing The Liver Model And The Use Thereof In Cytotoxicity Evaluation.
Inventors include Dobrzanski, Tomasz; Wszola, Michal; Klak, Marta; Domanski, Sylwester; and Kosowska, Katarzyna.
The application for the patent was published on July 31, 2026, under issue no. 31/2026.
Abstract: A bioprinted liver model with a vascular system consisting of layers and comprising at least one flow channel in which: the first two layers forming the base of the model are 100% filled with bioink, and wherein layer 1 is positioned at an angle of 0° to the flow channel and layer 2 is positioned at an angle of 90° to the flow channel, the inner layers of the model are filled from 20% to 100% with bioink, wherein the inner layers comprise a centrally located at least one flow channel, the perimeter of which is printed with 100% filling and in which every inner layer is arranged at an angle of 60° with respect to the previous layer, the last two layers enclosing the model: the penultimate and the last layer are 100% filled with bioink and wherein the penultimate layer is arranged at an angle of 0° with respect to the flow channel and the last layer is arranged at an angle of 90° with respect to the flow channel, wherein the bioink used is based on natural polymers, synthetic polymers, methacrylated derivatives of natural polymers or mixtures thereof. A method for manufacturing the liver model and the use thereof.
Disclaimer: Curated by HT Syndication.
