MUMBAI, India, Sept. 28 -- Intellectual Property India has published a patent application (202511018217 A) filed by Council Of Scientific And Industrial Research An Indian on February 28, 2025, for 2-Aminopyrimido[4',5':3,4]cyclohepta[1,2-B]indoles As Anti-Sars-Cov-2 Agent And Process For Preparation Thereof.

Inventors include Sandip Bibishan Bharate; Kiran Kumar Bokara; Bhagyashri Naganathrao Wadje; Alna Kuriyickal Martin; Yogesh Sardana; and Renuga Devi Muruganandham.

The application for the patent was published on September 25, 2026, under issue no. 39/2026.

Abstract: The present invention relates to the cyclic amine substituted 2-aminopyrimido[4',5':3,4]cyclohepta[1,2-b]indoles of general formula I wherein, n is selected from 0-3; X is selected from carbon and nitrogen and R represents cyclic amine (N in a ring) where ring can be variable as Ris a 6 to 8 membered cyclic amine such as e.g., azetidine, pyrrolidine, piperidine, azepane. The present invention particularly relates to synthesis and anti-SARS-CoV-2 inhibition activity of C11 substituted aminopyrimido[4',5':3,4]cyclohepta[1,2-b]indoles. In addition, the invention relates to methods of using compounds for treating or preventing SARS-CoV-2 infection.

Disclaimer: Curated by HT Syndication.