MUMBAI, India, Jan. 23 -- Intellectual Property India has published a patent application (202541116812 A) filed by Rajalakshmi Engineering College, Chennai, Tamil Nadu, on Nov. 25, 2025, for 'white-box machine learning system for cardiovascular risk prediction.'
Inventor(s) include Dr. M. Thangamani; and M. Subbaiya.
The application for the patent was published on Jan. 23, under issue no. 04/2026.
According to the abstract released by the Intellectual Property India: "The invention relates to a white box machine learning system for predicting cardiovascular risk using an interpretable logistic regression framework. The system processes multidimensional clinical data collected fiom the UCl Statlog Heart dataset, including age, resting blood pressure, serum cholesterol, chest pain type, thalassemia status and other key attributes. A preprocessing module cleans, encodes and standardizes the data within a 10-fold cross validation structure to ensure unbiased model development and prevent data leakage. The logistic regression model is trained using the caret package in R to estimate the probability of heart disease for each patient. The system provides transparent outputs through coefficient based interpretation and Variable Importance Plots, enabling clinicians to understand how each risk factor contributes to the final prediction. By prioritizing interpretability and methodological rigor, the invention supports early identification of al risk individuals and strengthens clinical decision making through a reliable and explainable decision support tool."
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