MUMBAI, India, Jan. 23 -- Intellectual Property India has published a patent application (202541126154 A) filed by Krishna Kumar Pathjil Damoderam Nair, Palakkad, Kerala, on Dec. 12, 2025, for 'vaginal drug composition comprising hydrochlorothiazide and dienogest for treatment of inflammatory pelvic cysts.'
Inventor(s) include Krishna Kumar Pathjil Damoderam Nair.
The application for the patent was published on Jan. 23, under issue no. 04/2026.
According to the abstract released by the Intellectual Property India: "This invention provides a novel, non-surgical therapeutic composition for managing inflammatory pelvic cysts through vaginal administration of hydrochlorothiazide (0.3-0.8 mg) and Dienogest (0.5-0.8 mg). Clinical benchmarks demonstrate that oral Dienogest reduces endometrioma volume and pain, yet systemic exposure and recurrence remain limitations. By combining localized anti-edematous and anti-proliferative effects, the disclosed composition reduces cystic fluid, suppresses cytokine activity, and improves pelvic tissue health while preserving fertility. The invention offers a safe, effective, and fertility-friendly alternative to invasive procedures, representing a significant advancement in gynaecological care."
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