MUMBAI, India, Nov. 21 -- Intellectual Property India has published a patent application (202521103480 A) filed by Pravin Badhe, Pune, Maharashtra, on Oct. 27, for 'ultrasonic-assisted extraction process for ocimum sanctum formulation for chemoprevention of breast cancer via antioxidant and tnf-a modulation.'
Inventor(s) include Dr Pravin Badhe; Mrs Ashwini Badhe; Merin Levy Philips; Dr. Santhosha Kulal; Dr. Yashodha Darshan; Dr. Vastvikta Sahai; and Dr. Sanjana A.
The application for the patent was published on Nov. 21, under issue no. 47/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to a standardized herbal suspension of Ocimum sanctum (Tulsi) formulated to achieve improved bioavailability, enhanced pharmacological stability, and consistent therapeutic efficacy. The formulation comprises Ocimum sanctum ethanolic extract (15% w/v), Tween 80 (1%), sodium carboxymethyl cellulose (1%), sodium benzoate (0.1%), and distilled water q.s. to 100%. The extract is prepared using ultrasonic-assisted extraction (UAE) with 95% ethanol at 50 kHz and 40 C for 50 minutes, ensuring maximal recovery and preservation of active phytoconstituents such as eugenol, ursolic acid, and rosmarinic acid. The combination of excipients ensures uniform dispersion, prevents sedimentation, and provides microbial stability, thereby extending shelf life. The suspension demonstrates significant antioxidant and anti-inflammatory activities, reducing oxidative stress markers and modulating inflammatory mediators. Stability studies confirm the formulation's physical and microbial integrity under ambient storage. The invention thus provides a safe, effective, and pharmaceutically stable herbal suspension suitable for long-term oral administration and modern phytopharmaceutical applications."
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