MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541123011 A) filed by Vellore Institute Of Technology, Vellore, Tamil Nadu, on Dec. 5, 2025, for 'transcriptome-wide association study method for alzheimer's disease gene identification.'
Inventor(s) include Dr. R. Sudesh; Mr. Sudarshan Gopinath; and Mr. Shehzail Abbas.
The application for the patent was published on Jan. 2, under issue no. 01/2026.
According to the abstract released by the Intellectual Property India: "The present disclosure provides a computer-implemented method (100) for identifying candidate genes associated with Alzheimer's disease. The method (100) includes obtaining genome-wide association study summary statistics from an AMP-AD Knowledge Portal in a step (102), acquiring hippocampal gene expression reference data from a GTEx v8 Brain Hippocampus dataset in a step (104), downloading linkage disequilibrium reference data from a 1000 Genomes European ancestry population in a step (106), executing a TWAS-FUSION framework to integrate the genome-wide association study summary statistics with hippocampal expression weights in a step (110), and generating transcriptome-wide association test statistics for all genes across chromosomes 1-22 in a step (114) to identify candidate genes associated with Alzheimer's disease."
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