MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202531105997 A) filed by Dr. Kakali Bhadra, Nadia, West Bengal, on Nov. 2, 2025, for 'tick repellent formulation from plant-based active compounds.'

Inventor(s) include Dr. Kakali Bhadra; Ms. Alivia Mandal; and Dr. Bishwajeet Paul,.

The application for the patent was published on March 13, under issue no. 11/2026.

According to the abstract released by the Intellectual Property India: "Tick repellent formulation from plant-based active compounds The present invention discloses a plant-based tick repellent formulation comprising citronellal, eugenol, and geranyl butyrate in specific ratios, combined with suitable inert excipients including carrier, emulsifier, stabilizer, and thixotropic agent. The optimized formulation contains approximately 30% active ingredients in the ratio of 4:1:1 (Citronellal:Eugenol:Geranyl Butyrate) and 70% inert excipients, resulting in a stable lotion with enhanced repellency and shelf-life. The formulation demonstrates broad-spectrum activity against multiple economically important tick species, namely Haemaphysalis darjeeling, Rhipicephalus (Boophilus) microplus, Hyalomma anatolicum anatolicum, and Amblyomma hebraeum. Experimental bioassays confirmed that the formulation provides superior repellency compared to conventional synthetic repellents such as dimethyl phthalate (DMP), with prolonged efficacy up to 3.5-4 hours. Cytotoxicity testing using the MTT assay on human epithelial cell line WRL-68 established that the active ingredients are safe at working concentrations, with negligible cytotoxic effects. The invention thus provides a sustainable, eco-friendly, and safe alternative to synthetic acaricides, minimizing environmental hazards while ensuring effective tick management in livestock."

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